Why Do I Need an Injection in My Eye?
There are some eye conditions where your doctor might recommend an eye injection as a treatment option.
Injections into the eye, specifically into the vitreous or gel-filled cavity of the eye, are called intravitreal injections.
Anti-vascular endothelial growth factors (anti-VEGF) are probably the most commonly injected agents. They are used to treat wet age-related macular degeneration (ARMD), diabetic retinopathy, and retinal vein occlusion.
In these conditions, there are abnormal leaky blood vessels that cause fluid and blood to accumulate in and under the retina. This accumulation of fluid results in loss of central vision. The role of anti-VEGF agents is to shrink these abnormal vessels and restore the normal architecture of the retina.
There are three anti-VEGF agents widely administered: Lucentis, Avastin, and Eylea.
Lucentis (Ranibizumab) is FDA approved for treatment of wet ARMD, diabetic retinopathy, and vein occlusion. It is specially designed for injection into the eye and is a smaller molecule than Avastin so it may have better penetration into the retina.
Avastin (Bevacizumab) was originally approved by FDA for treating colorectal cancer. It […]